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Black Cobra Tablets in Pakistan (Sildenafil), sold as the brand name Black Cobra Tablets in Pakistan among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Black Cobra Tablets in Pakistan is unclear if it is effective for treating sexual dysfunction in women. Black Cobra Tablets in Pakistan is taken by mouth or injection into a vein. Onset is typically within 20 minutes and lasts for about 2 hours.
Black Cobra Tablets in Pakistan (Sildenafil) acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. Black Cobra Tablets in Pakistan requires sexual arousal, however, to work. Black Cobra Tablets in Pakistan also results in dilation of the blood vessels in the lungs.
Black Cobra Tablets in Pakistan originally discovered the medication in 1989 while looking for a treatment for heart-related chest pain. It was approved for medical use in the United States and Europe in 1998. In the United States about 2 million prescriptions were written for Sildenafil in 2016. In 2017 it became available as a generic medication. In the United Kingdom it is available over the counter.
The primary indication of Black Cobra Tablets in Pakistan (Sildenafil) is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus.
In clinical trials, the most common adverse effects of Sildenafil use included headache, flushing, indigestion, nasal congestion, and impaired vision, including photophobia and blurred vision. Some Sildenafil users have complained of seeing everything tinted blue (cyanosis). Some complained of blurriness and loss of peripheral vision. In July 2005, the FDA found that Sildenafil could lead to vision impairment in rare cases and a number of studies have linked Sildenafil use with non-arthritic anterior ischemic optic neuropathy.
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